The Department of Stem Cell and Regenerative Biology (SCRB) is the first cross-school department located in both the Faculty of Arts and Sciences and Harvard Medical School. The Department's focus is the development, maintenance and repair of vertebrate tissues. Emphasis is placed on using these aspects of biology to inform the understanding of human diseases.

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A Wrights Giemsa stained human embryonic stem cell (hESC) colony (H9) on murine embryonic fibroblast (MEF) feeder cells at high magnification. The colony contains roughly 50-70... more

3D reconstruction showing the spatial distribution of blood vessels (red), osteoblasts (green) and bone (blue) in the bone marrow cavity.

Chromosomes being extracted from a fertilized ova, or zygote. The blue mass in the pipette is the chromosomes that have been removed from the zygote.

During kidney development, new nephrons are induced by an interaction between the ureteric epithelium and the metanephric mesenchyme. At the tip of the ureteric bud epithelium the... more

Undergraduate student participating in the HSCI Internship Program

Single brightly labeled HSC (white) captured within the bone marrow cavity of an irradiated recipient mouse (blue:bone, green: osteoblasts, red: vasculature) one hour after... more

Intern in the HSCI Internship Program

Maturing neurons labeled in green expressing prion protein (red). Click... more

A sagittal section of the murine brain showing corticofugal cortical projection neuron axons leaving the cortex and descending to subcortical and subcerebral targets. more

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